Telkines and Hades

Need keys that drop from end of Acts bosses.

No idea, never used it due to the long cooldown, but if you have Nature then using Refresh will shorten that cooldown time.

Nothing in Rogue to benefit pets much.

I changed your link a bit.  Max Overgrowth and Refresh, drop Regrowth line and Tranquility of Water, as one pointers they're not worth it.

https://www.tqcalc.com/TitanCalcd6f4d6f4d6f4.html?mastery=Ritualist&master1=4&master2=9&sa=30&m1=40-0-0-12-0-0-8-0-0-8-0-0-0-16-6-0-12-8-12-0-12-0-8-0-0-0&m2=32-0-12-0-0-8-12-6-16-8-8-0-12-8-0-0-6-0-0-8-0-0-0-0-0-0

Live stream on Monday, 25th November to show off the new Berserker mastery coming in the Fangs of Asterkarn expansion next year.

1pm EST, 6pm GMT, 7pm CET

https://forums.crateentertainment.com/t/join-us-for-a-livestream-on-november-25th/141427

Sorry, I still don't know what you mean.  Do you have a screenshot you could link here?

Do you mean how long a character has been played in the game?

Try the following:

Turn off Steam Cloud for Titan Quest Anniversary Edition
This concerns people playing on: Steam, GoG, Microsoft Store, Epic Games
Between each of the steps, try to run the game and check if your bug is fixed

Steps
🇦  Restart the store client and make sure you're connected to the internet. (Steam, GoG, Epic Games)
🇧  Run TQ.exe in admin mode.
🇨  Verify files with the store client you're using (e.g. Steam)
🇩  Restart computer
🇪  Update the graphics card (GPU) drivers
🇫  Update Windows
🇬  Reinstall the game and delete all folders and files related to TQ. (make backups of your save files first).
🇭  Reinstall Microsoft .NET Framework (see guide on internet)
🇮  Reinstall Visual C++ Redistributable (see guide on internet)