This guide also appears in KP but is so helpful this deserves it's own thread in this new dedicated TQ forum:

Resistance reduction comes in 2 flavors , absolute and percentage.

In the absolute case , the target’s resistance goes to ; original – debuff.

In the percentage case , it goes to ; original*(1-debuff%).

If the target’s resistance is negative ; original*(1+debuff%)

The 2 effects (percentage and absolute) are NOT always labeled correctly in the game.

Things with a percentage reduction ;

– All skills that reduce all resistances (ToW , soul blight , squall)

– weapons “of the betrayer”

– some epics/legendaries

Things with an absolute reduction ;

– All skills that reduce specific resistances (study prey , necrosis , triumph , plague)

– dark medicine and monkey king relics

– some epics/legendaries

As far as I see , percentage and absolute reduction are correctly labeled when they appear on most equipment.

So you know what you are getting when you pick up a sapros or pyrophoric lop.

If it is not obvious , percentage reduction has no effect on a 0% resistance.

It is possible to push resistances negative with percentage reduction , but good luck stacking 100%+ of percentage effects.

So for example if you hit a target with study prey (-50) , you’ll reduce his resistance to physical and piercing by 50 points = a 70% resistance will become a 20% resistance.

If you use squall (-30%) you’ll reduce his resistance by 30% = a resistance of 70% will become 49%.

STACKING

Now this is the complicated part.

GEAR

For effects on gear just add them all up apart from the ones on weapons and shields.

If both weapon and shield (or weapon and weapon) have the same type of effect (like both having absolute reduction) then only the stronger one will apply.

If they have different types of effects then they’ll both work.

You need to hit the opponent with the weapon/shield that has the debuff on it for it to work.

The effect is not shared by the weapons and the same goes for shields

So add the weapons effect (or effects) to your total , for a x absolute and y percentage total reduction.

These stack up as already discussed ; resist = orig_resist*(1 – pc_debuff) – abs_debuff.

SKILLS

For a start , multiple skills with percentage reduction DO NOT stack (or so it seems).

Yes , that’s right , squall and ToW don’t stack.

Only the strongest will apply.

Multiple skills with absolute reduction do stack.

Combining skills with different types?

In this case the absolute reduction happens BEFORE the percentage one.

So it’s ; resist = (orig_resist – abs_debuff)*(1 – pc_debuff)

SKILLS AND GEAR

Here is where I almost went insane.

For a start , percentage debuffs from gear don’t stack with percentage debuffs from skills , the stronger one is applied.

Absolute debuffs from gear stack with everything.

Then there’s the order.

Apparently skills get applied before gear , that simple.

It doesn’t matter what kind of reduction you have.

Which leads to this if you have percentage and absolute effects from both gear and skills.

resist = (orig_resist – skill_abs_debuff)*(1 – pc_debuff) – gear_abs_debuff

Where the “pc_debuff” is what you get from gear or what you get from a skill , whichever is larger.

BIG EXAMPLE

You (somehow) have study prey (-50) , plague (-39) , ToW (-30%) , sapros the corrupter (-60) and a weapon “of the betrayer” (-40%).

And you use them all to nuke an opponent with a 30% physical resistance.

For a start , check the gear.

The 2 weapons don’t have the same effect , one is absolute the other percentage , so they stack.

A total of -60 and -40%.

There are 2 absolute and 1 percentage skill , so they stack.

A total of -89 and -30%.

Then combine the 2 ; absolute effects always stack , but the percentages from gear and skills DON’T.

The total effect from gear is -40% , the one from skills is -30% , so the one from gear will apply because it’s stronger.

And for the total calculation

1) absolute reduction from skills

resist = 30% – 89% = -59%

2) percentage reduction from skills ; we don’t have any , it’s overriden by the betrayer weapon.

3) percentage reduction from gear , because the resistance is already negative we use a + instead of a -.

resist = -59%*(1+40%) = -83%.

4) absolute reduction from gear

resist = -83% – 60% = -143%

END OF BIG EXAMPLE

If there is a lower limit to how far negative you can push an opponent’s resistance then it must be very low.

I’ve pushed an opponent’s resistance below -1000% and it still worked.

KP linkPersonal Sidenotes (by botebote77):

1) This guide was written for TQIT but is still true for TQAE/R

2) When comparing the three skills that give resistance reduction (squall, study prey, and susceptibility), study prey and susceptibility both give absolute resistance reduction and so is better in terms of lowering a resistance as low as possible.. However, squall reduces all resistances so squall might be best if you deal many different types of damages

3) In the case of spreading resistance reduction through attack skills, i found ternion, throwing knife, and thunder strike with 2 throwing weapons equipped to be the best..

**Do not** make the same mistake as i did by selling all my the frail.. The resistance reduction given by it is absolute and is a whopping flat 30.. If you get lucky enough to find Twisted Coil of the Parasite, it should be a no brainer that you should keep it.

4) Wherever you are now apocalyse80 good sir, domo arigatou gozaimasu