Typhon allll the way. I remember my first character being a soothsayer (nature+spirit). A really strong combo right? Well, no, it wasn't, not in the noobish way i built that guy. I went all strength (no dex), i had some points in auras and the lich pet (but maxed out the + on each mastery), i did not farm items and skipped areas (so my level was below 30). The moment i got next to it, the guy slapped me so bad that my character went flying back to helos. And no, that character never got to finish the game...and we are talking normal here.
In my defense, i was 15y old, my english was kinda bad and got the game months after i got my first pc. So, getting all the way up to Typhon was an accomplishment for me.
Now, i crush that guy in xmax but the ptsd is still there.