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i said on another topic that if you have corselet of freyja, archmages clasp and something of the mammoth helm with +2 erebus, that it's reason enough to go hybrid stat for just about any character.. i still stand with that.. vit also scales with int and necrosis + circle of power is crazy vit damage
if you are going for immunity builds, more item choices makes it easier.. although it's also possible with only str and dex if you spend enough time researching (like what you did)
Vitality dmg can't crit, Physical dmg can.Vitality will have trouble when fight some kind of enemies, boss more than Physical dmg.For character that melee dmg, i think physical melee better than hybrid or full int melee at all.