Em, not quite, warfare is physical damage melee mastery, rune is for elemental damage attacks but this kind of attacks wasn't supported in the base game initially. Rune mastery was supposed to introduce a simple way to circumvent that.
Berserker you would either need to build as pure physical, but in this case you lose a lot of what rune has to offer for damage. Or elemental melee, but that is not an easy build for beginner.
Easy dw melee for beginner is harbinger, warfare + dream. Most simple OP starter build is mace + shield conqueror. For spears it is haruspex or brigand. For bows it is haruspex or ranger. Throwing weapons would be dragon hunter or stonespeaker. And caster either druid or summoner.
https://www.kirmiziperfect.com/titancalc-anniversary-edition/index-2.htmlIf you insist on doing a berserker, make it physical damage with support only from rune.